Sunday, February 6, 2011

PIH

General
This case presentation aims to identify and determine the general health problems and needs of the patient with an admitting diagnosis of Pregnancy Induced Hypertension. This presentation also intends to help patient promote health and medical understanding of such condition through the application of the nursing skills.
Specific
  • To raise the level of awareness of patient on health problems that she may encounter.
  • To facilitate patient in taking necessary actions to solve and prevent the identified problems on her own.
  • To help patient in motivating her to continue the health care provided by the health workers.
  • To render nursing care and information to patient through the application of the nursing skills.
INTRODUCTION

Blood pressure is the force of the blood pushing against the walls of the arteries (blood vessels that carry oxygen-rich blood to all parts of the body). When the pressure in the arteries becomes too high, it is called hypertension.

Up to 5 percent of women have hypertension before they become pregnant .  This is called chronic hypertension. Another 5 to 8 percent develop hypertension during pregnancy. This is referred to as gestational hypertension. Gestational hypertension generally goes away soon after delivery: however, women who develop it may be at increased risk of developing hypertension later in life.

High blood pressure usually causes no noticeable symptoms, whether or not a woman is pregnant. However, hypertension during pregnancy can cause serious complications for mother and baby. Fortunately, serious problems usually can be prevented with proper prenatal care.
Anatomy and Physiology:
When most people hear the term cardiovascular system, they immediately think of the heart. We have all felt our own heart "pound" from time to time, and we tend to get a bit nervous when this happens. The crucial importance of the heart has been recognized for a long time. However, the cardiovascular system is much more than just the heart, and from a scientific and medical standpoint, it is important to understand why this system is so vital to life.
Most simply stated, the major function of the cardiovascular system is transportation. Using blood as the transport vehicle, the system carries oxygen, nutrients, cell wastes, hormones, and many other substances vital for body homeostasis to and from the cells. The force to move the blood around the body is provided by the beating heart. The cardiovascular system can be compared to a muscular pump equipped with one-way valves and a system of large and small plumbing tubes within which the blood travels.
HEART:
The heart is a muscular organ found in all vertebrates that is responsible for pumping blood throughout the blood vessels by repeated, rhythmic contractions.
The heart is enclosed in a double-walled sac called the pericardium. The superficial part of this sac is called the fibrous pericardium. This sac protects the heart, anchors its surrounding structures, and prevents overfilling of the heart with blood. It is located anterior to the vertebral column and posterior to the sternum. The size of the heart is about the size of a fist and has a mass of between 250 grams and 350 grams. The heart is composed of three layers, all of which are rich with blood vessels. The superficial layer, called the visceral layer, the middle layer, called the myocardium, and the third layer which is called the endocardium. The heart has four chambers, two superior atria and two inferior ventricles. The atria are the receiving chambers and the ventricles are the discharging chambers. The pathway of blood through the heart consists of a pulmonary circuit and a systemic circuit. Blood flows through the heart in one direction, from the atrias to the ventricles, and out of the great arteries, or the aorta for example. This is done by four valves which are the tricuspid atrioventicular valve, the mitral atrioventicular valve, the aortic semilunar valve, and the pulmonary semilunar valve.
Systemic circulation is the portion of the cardiovascular system which carries oxygenated blood away from the heart, to the body, and returns deoxygenated blood back to the heart. The term is contrasted with pulmonary circulation.
Pulmonary circulation is the portion of the cardiovascular system which carries oxygen-depleted blood away from the heart, to the lungs, and returns oxygenated blood back to the heart. The term is contrasted with systemic circulation. A separate system known as the bronchial circulation supplies blood to the tissue of the larger airways of the lung.
Arteries are blood vessels that carry blood away from the heart. All arteries, with the exception of the pulmonary and umbilical arteries, carry oxygenated blood.
Pulmonary arteries
The pulmonary arteries carry deoxygenated blood that has just returned from the body to the heart towards the lungs, where carbon dioxide is exchanged for oxygen.
Systemic arteries
Systemic arteries can be subdivided into two types – muscular and elastic – according to the relative compositions of elastic and muscle tissue in their tunica media as well as their size and the makeup of the internal and external elastic lamina. The larger arteries (>10mm diameter) are generally elastic and the smaller ones (0.1-10mm) tend to be muscular. Systemic arteries deliver blood to the arterioles, and then to the capillaries, where nutrients and gasses are exchanged.
The Aorta
The aorta is the root systemic artery. It receives blood directly from the left ventricle of the heart via the aortic valve. As the aorta branches, and these arteries branch in turn, they become successively smaller in diameter, down to the arteriole. The arterioles supply capillaries which in turn empty into venules. The very first branches off of the aorta are the coronary arteries, which supply blood to the heart muscle itself. These are followed by the branches off the aortic arch, namely the brachiocephalic artery, the left common carotid and the left subclavian arteries.
Aorta the largest artery in the body, originating from the left ventricle of the heart and extends down to the abdomen, where it branches off into two smaller arteries (the common iliacs). The aorta brings oxygenated blood to all parts of the body in the systemic circulation.
The aorta is usually divided into five segments/sections:
  • Ascending aorta—the section between the heart and the arch of aorta
  • Arch of aorta—the peak part that looks somewhat like an inverted "U"
  • Descending aorta—the section from the arch of aorta to the point where it divides into the common iliac arteries
    o    Thoracic aorta—the half of the descending aorta above the diaphragm
    o    Abdominal aorta—the half of the descending aorta below the diaphragm
Arterioles
Arterioles, the smallest of the true arteries, help regulate blood pressure by the variable contraction of the smooth muscle of their walls, and deliver blood to the capillaries.
Veins are blood vessels that carry blood towards the heart. Most veins carry deoxygenated blood from the tissues back to the lungs; exceptions are the pulmonary and umbilical veins, both of which carry oxygenated blood. Veins differ from arteries in structure and function; for example, arteries are more muscular than veins and they carry blood away from the heart.
Veins are classified in a number of ways, including superficial vs. deep, pulmonary vs. systemic, and large vs. small.
Superficial veins
Superficial veins are those whose course is close to the surface of the body, and have no corresponding arteries.
Deep veins
Deep veins are deeper in the body and have corresponding arteries.
Pulmonary veins
The pulmonary veins are a set of veins that deliver oxygenated blood from the lungs to the heart.
Systemic veins
Systemic veins drain the tissues of the body and deliver deoxygenated blood to the heart.
Atrium sometimes called auricle, refers to a chamber or space. It may be the atrium of the lateral ventricle in the brain or the blood collection chamber of a heart. It has a thin-walled structure that allows blood to return to the heart. There is at least one atrium in animals with a closed circulatory system.
Right atrium is one of four chambers (two atria and two ventricles) in the human heart. It receives deoxygenated blood from the superior and inferior vena cava and the coronary sinus, and pumps it into the right ventricle through the tricuspid valve. Attached to the right atrium is the right auricular appendix.
Left atrium is one of the four chambers in the human heart. It receives oxygenated blood from the pulmonary veins, and pumps it into the left ventricle, via the atrioventricular valve.
Ventricle is a chamber which collects blood from an atrium (another heart chamber that is smaller than a ventricle) and pumps it out of the heart.
Right ventricle is one of four chambers (two atria and two ventricles) in the human heart. It receives deoxygenated blood from the right atrium via the tricuspid valve, and pumps it into the pulmonary artery via the pulmonary valve and pulmonary trunk.
Left ventricle is one of four chambers (two atria and two ventricles) in the human heart. It receives oxygenated blood from the left atrium via the mitral valve, and pumps it into the aorta via the aortic valve.

Clinical Manifestations:
A.  Mild Preeclampsia
  • BP of 140/90
  • 1+ to 2+ proteinuria on random
  • weight gain of 2 lbs per week on the 2nd trimester and 1 lb per week on the 3rd trimester
  • Slight edema in upper extremities and face
B. Severe Preeclampsia
  • BP of 160/110
  • 3-4+ protenuria on random
  • Oliguria (less than 500 ml/24 hrs)
  • Cerebral or visual disturbances
  • Epigastric pain
  • Pulmonary edema
  • Peripheral edema
  • Hepatic dysfunction
C. Eclampsia is an extension of preeclampsia and is characterized by the client experiencing seizures.

Diagnostic Evaluation:
  1. Based on the presenting symptoms. Often the disease process has been developing and affecting the renal and vascular system
  2. Frequently a sudden weight gain will occur, of 2 lb. or more in 1 week, or 6 lb. or more within 1 month. This often occurs before the edema is present.

DISEASE ENTITY
Pregnancy induced hypertension (PIH) is a condition of high blood pressure during pregnancy. Your blood pressure goes up, you retain water, and protein is found in your urine. It is also called toxemia or preeclampsia. The exact cause of PIH is unknown.
Pregnancy-induced hypertension (PIH) is a form of high blood pressure in pregnancy. It occurs in about 7 to 10 percent ofall pregnancies. Another type of high blood pressure is chronic hypertension - high blood pressure that is present before pregnancy begins.
With high blood pressure, there is an increase in the resistance of blood vessels. This may hinder blood flow in many different organ systems in the expectant mother including the liver, kidneys, brain, uterus, and placenta.
Eclampsia is a severe form of pregnancy-induced hypertension. Women with eclampsia have seizures resulting from the condition. Eclampsia occurs in about one in 1,600 pregnancies and develops near the end of pregnancy, in most cases.

Causes pregnancy-induced hypertension (PIH)?
The cause of PIH is unknown. Some conditions may increase the risk of developing PIH, including the following:

  • pre-existing hypertension (high blood pressure).

  • kidney disease.

  • diabetes.

  • PIH with a previous pregnancy.

  • mother's age younger than 20 or older than 40.

  • multiple fetuses (twins, triplets).


The following are the most common symptoms of high blood pressure in pregnancy. However, each woman may experience symptoms differently. Symptoms may include
  • increased blood pressure.

  • protein in the urine.

  • edema (swelling).

  • sudden weight gain.

  • visual changes such as blurred or double vision.

  • nausea, vomiting.

  • right-sided upper abdominal pain or pain around the stomach.

  • urinating small amounts.

  • changes in liver or kidney function tests

How is pregnancy-induced hypertension diagnosed?
Diagnosis is often based on the increase in blood pressure levels, but other symptoms may help establish PIH as the diagnosis. Tests for pregnancy-induced hypertension may include the following:

  • blood pressure measurement

  • urine testing.

  • assessment of edema.

  • frequent weight measurements.

  • eye examination to check for retinal changes.

  • liver and kidney function tests.

Treatment for pregnancy-induced hypertension:
Specific treatment for pregnancy-induced hypertension will be determined by your physician based on:

  • your pregnancy, overall health and medical history.

  • extent of the disease.

  • your tolerance for specific medications, procedures, or therapies

The goal of treatment is to prevent the condition from becoming worse and to prevent it from causing other complications.
Treatment for pregnancy-induced hypertension (PIH) may include:

  • bedrest (either at home or in the hospital may be recommended).

  • hospitalization (as specialized personnel and equipment may be necessary).

  • magnesium sulfate (or other antihypertensive medications for PIH).

  • fetal monitoring (to check the health of the fetus when the mother has PIH) may include:

  • Doppler flow studies - type of ultrasound that uses sound waves to measure the flow of blood through a blood vessel.

  • medications, called corticosteroids, that may help mature the lungs of the fetus (lung immaturity is a major problem of premature babies)
  • delivery of the baby (if treatments do not control PIH or if the fetus or mother is in danger). Cesarean delivery may be recommended, in some cases
Medical Treatment and Evaluation:
  1. Magnesium Sulfate (Pregnancy risk category B)
      muscle relaxant, prevent seizures
      loading dose 4-6g, maintenance dose 1-2g/h IV
      infuse IV dose slowly over 15-30 min.
       •Always administer as a piggy back infusion.
       •Assess PR, urine output, DTR, and clonus every hour.
       •Observe for CNS depression and hypotonia in infant at birth.
  2. Hydrazaline (Apresoline) Pregnancy risk category C
      anti hypertensive (peripheral vasodilator) use to decrease hypertension
      5-10mg/IV
      Administer slowly to avoid sudden fall of BP
       •Maintain diastolic pressure over 90 mmHg to ensure adequate placental filling.
  3. Diazepam (Valium) Pregnancy risk category D
      halt seizures
      5-10mg/IV
      administer slowly. Dose may be repeated every 10-15 min. (up to 30mg/hr)
       •Observe for respiratory depression for both mother and infant at birth.
  4. Calcium Gluconate (Pregnancy risk category C)
      antidote for Magnesium Sulfate
      1g/IV (10 mL of a 10% solution)
      have prepared at bed side when administering Magnesium Sulfate
      administer at 5mL/min.


 Discharge Planning:
Exercise
  1. encourage patient’s on deep breathing exercises.
  2. move extremities when lying.
  3. elevate the head part when sleeping, to promote increase peripheral circulation
  4. encourage overall passive and active exercises program during pregnancy to prevent need for cesarean birth.
  5. exercises like tailor sitting, squatting, kegel exercise, pelvic rocking, and abdominal muscle contraction will promote easy delivery. 
Treatment:
  1. use of drugs
  2. catheterization
  3. obtaining labs. (CBC, platelets count, liver function, BUN and creatinine, and fibrin degregation)
Health Teaching:
  1. Encourage patient foe sodium restriction.
  2. Encourage to avoid foods rich in oil and fats.
  3. Encourage patient to limit her daily activities and exercises.
Ongoing Assessment:
  1. Observe carefully for symptoms at prenatal visit.
  2. Give instruction about what symptoms to watch for so she can alert her clinician if additional symptoms occur between visits.
Diet:
  1. low fats and sodium diet, restriction if possible.
  2. high in protein, calcium and iron.
  3. Adequate fluid intake
Sex:
  1. limit sexual activity
  2. sexual intercourse at 2nd trimester should be avoided. 

Sunday, January 30, 2011

CERVICAL CANCER

I.   OBJECTIVES:
General Objective:
       To be able to know and learn more about the disease, cervical cancer,
    Specific Objectives:
1.           To render proper nursing care to the patient.
2.          To help patient as well as the family to know ways on how to handle situations pertaining to the disease.
3.          To be able to know how the disease occur.
4.          To know the pathophysiology of the disease.
5.          To be familiarized with the anatomy and physiology of the organ involved.

I.   MEDICAL DIAGNOSIS

Cervical cancer is malignant neoplasm of the cervix uteri or cervical area. It may present with vaginal bleeding, but symptoms may be absent until the cancer is in its advanced stages. Treatment consists of surgery (including local excision) in early stages and chemotherapy and radiotherapy in advanced stages of the disease.
Cervical cancer occurs when abnormal cells on the cervix grow out of control. The cervix is the lower part of the uterus that opens into the vagina. Cervical cancer can often be cured when it’s found early. It is usually found at a very early stage through a Pap test.
Cervical cancer begins in cells on the surface of the cervix. Over time, the cervical cancer can invade more deeply into the cervix and nearby tissues. The cancer cells can spread by breaking away from the original (primary) tumor. They enter blood vessels or lymph vessels, which branch into all the tissues of the body. The cancer cells may attach to other tissues and grow to form new tumors that may damage those tissues. The spread of cancer is called metastasis. See the Staging section for information about cervical cancer that has spread.

Causes & Risk Factors

Cervical cancers start in the cells on the surface of the cervix. There are two types of cells on the cervix's surface: squamous and columnar. The majority of cervical cancers are from squamous cells.
The development of cervical cancer is usually very slow. It starts as a pre-cancerous condition called dysplasia.
Almost all cervical cancers are caused by HPV (human papilloma virus). HPV is a common virus that is spread through sexual intercourse. There are many different types of HPV, and many do not cause problems. However, only certain strains of HPV actually lead to cervical cancer. (Other strains may cause genital warts.)
Other risk factors for cervical cancer include:
  • Having sex at an early age
  • Multiple sexual partners
  • Sexual partners who have multiple partners or who participate in high-risk sexual activities
  • Women whose mothers took the drug DES (diethylstilbestrol) during pregnancy in the early 1960s to prevent miscarriage
  • Weakened immune system
  • Poor economic status (may not be able to afford regular Pap smears)
  • Using birth control pills for more than 5 years. This may be related to infection with HPV.5
  • Exposure to diethylstilbestrol (DES) before birth (prenatal exposure), though this is rare.
  • Smoking or a history of smoking, and possibly exposure to secondhand smoke.

Symptoms

Most of the time, early cervical cancer has no symptoms. Symptoms that may occur can include:
  • Continuous vaginal discharge, which may be pale, watery, pink, brown, bloody, or foul-smelling
  • Abnormal vaginal bleeding between periods, after intercourse, or after menopause
  • Periods become heavier and last longer than usual
  • Any bleeding after menopause
  • Bleeding when something comes in contact with the cervix, such as during sexual intercourse or when you insert a diaphragm.
  • Pain during sexual intercourse.
  • Abnormal vaginal discharge containing mucus that may be tinged with blood.
Symptoms of advanced cervical cancer may include:
  • Loss of appetite
  • Weight loss
  • Fatigue
  • Pelvic pain
  • Back pain
  • Leg pain
  • Single swollen leg
  • Heavy bleeding from the vagina
  • Leaking of urine or feces from the vagina
  • Bone fractures
  • Anemia because of abnormal vaginal bleeding.
  • Urinary problems because of blockage of a kidney or urether.
  • Leakage of urine or fecal content into the vagina because an abnormal opening (fistula) has developed between the vagina and the bladder or rectum.


Staging

Cervical cancer is staged by the International Federation of Gynecology and Obstetrics (FIGO) staging system, which is based on clinical examination, rather than surgical findings. It allows only the following diagnostic tests to be used in determining the stage: palpation, inspection, colposcopy, endocervical curettage, hysteroscopy, cystoscopy, proctoscopy, intravenous urography, and X-ray
examination of the lungs and skeleton, and cervical conization.        

I.       ANATOMY AND PHYSIOLOGY
Female Reproductive System

The organs of the female reproductive system produce and sustain the female sex cells (egg cells or ova), transport these cells to a site where they may be fertilized by sperm, provide a favorable environment for the developing fetus, move the fetus to the outside at the end of the development period, and produce the female sex hormones. The female reproductive system includes the ovaries, Fallopian tubes, uterus, vagina, accessory glands, and external genital organs.

The organs of the female reproductive system produce and sustain the female sex cells (egg cells or ova), transport these cells to a site where they may be fertilized by sperm, provide a favorable environment for the developing fetus, move the fetus to the outside at the end of the development period, and produce the female sex hormones. The female reproductive system includes the ovaries, Fallopian tubes, uterus, vagina, accessory glands, and external genital organs.

external female genitalia

Part of the female reproductive system. The external genitalia are the accessory structures of the female reproductive system that are external to the vagina. They are also referred to as the vulva or pudendum. The external genitalia include the labia majora, mons pubis, labia minora, clitoris, and glands within the vestibule.

The clitoris is an erectile organ, similar to the male
penis, that responds to sexual stimulation. Posterior to the clitoris, the urethra, vagina, paraurethral glands and greater vestibular glands open into the vestibule.

cervix
A small, cylindrical organ, several centimeters long and less than 2.5cm (1 inch) in diameter, which comprises the lower part and neck of the uterus. The cervix separates the body and cavity of the uterus from the vagina. Running through the cervix is a canal, through which sperm can pass from the vagina into the uterus and through which blood passes during menstruation. The cervical canal, which forms part of the birth canal during childbirth, dilates (expands) widely to allow passage of a baby.

The bulk of the cervix consists if fibrous tissue with some
smooth muscle. This tissue makes the cervix into a form of sphincter (circular muscle) and allows for the great adaptability in its size and shape required during pregnancy and childbirth.

I.       MEDICAL MANAGEMENT

Surgical management of cervical cancer

Choice of the appropriate surgical procedure depends on the stage and the site of the cervical cancer. The diverse surgeries and forms of treatments used are:
  1. Conization: This procedure involves the removal of a cone shaped piece of the cervical tissue for examination and investigation. This procedure is done if PAP tests reveal the presence of precancerous cells.
  2. Hystrectomy: A procedure which entails the removal of the cervix and the uterus. There are further sub types – a vaginal hysterectomy (extraction of the uterus and the cervix through the vagina), a total abdominal hysterectomy (removal of the uterus and the cervix through a large abdominal incision), and a laproscopic hysterectomy (removal of the uterus and the cervix through a small incision in the abdomen and using a laproscope). More about Hystrectomy Surgery Abroad
  3. Bilateral salpingo-oophorectomy: A surgery that entails the removal of the fallopian tubes and the ovaries (components of the female reproductive system).
  4. Radical hysterectomy: This surgical procedure, removes the uterus, cervix, and a part of the vagina. Furthermore, the lymph nodes in the pelvic region are also dissected. The ovaries are spared.
  5. Pelvic exentration: This procedure calls for the removal of the cervix, uterus, vagina, ovaries, lymph nodes, lower colon, rectum, and bladder. Artificial openings are made for the elimination of urine and feces in to a collection bag. Plastic surgery can be resorted to for the reconstruction of an artificial vagina. More about total pelvic exenteration abroad.
  6. Cryosurgery: An advanced procedure, it involves the freezing and destruction of the cancerous tissue. It is advocated in the management of pre-invasive cancers.
  7. Laser surgery: A laser beam is used as a knife to make blood-less incisions to excise smaller abnormal tissues.
  8. Loop electro-surgical excision procedure (LEEP): An electrical current passes through a thin wire loop that acts as a knife to excise out abnormal tissue.
  9. Radiotherapy: In cases, where the carcinoma has spread beyond the cervix and surgical intervention alone cannot suffice, radiotherapy becomes necessary. Radiotherapy also promises a prevention of recurrence. Both internal and external radiotherapy are utilized. The therapy cycles are 5 days a week for a period of 6 weeks. Certain side effects of the treatment are hair loss, fatigue, nausea, diarrhea, and dysuria. Stages 1B and 2A show 85 to 90 % 5 year cure rates, 2B shows 60 to 65 %, stage 3 shows 25 to 40 % cure rates, and 4 shows 15 to 20 % cure rates.
  10. Chemotherapy: Chemotherapy is used to destroy cancer cells remaining after surgery. Chemotherapy may be given before the therapy, and then after the therapy to ensure that no cancer cells are left behind. The drugs are given through a series of injections. Side effects of the therapy are loss of appetite, nausea, vomiting, diarrhea, fatigue, headaches, and dysuria. More about chemotherapy abroad.
DISCHARGE PLANNING:
1.     Educate the patient and the family about the proper medications the patient should take to help manage the disease.
2.    Instruct the patient the types of work she is allowed to do and the activities she is prohibited to do.
3.    Advise the patient to go to the hospital for follow up checkups.
4.    Instructed the patient to eat nutritious and healthy foods.
5.    Advise the patient not to work to hard so as not to abuse herself.
6.    Advised the patient not to stop taking the medications prescribed to her.